Biotechnology Guidance and Resources
Guides and Resources With Pending Revisions
- Guide for Submitting Confidential Business Information (315.59 KB)
- Permit User Guide (948.53 KB)
- Guide to Submitting Data for Reports and Notices in APHIS eFile (892.55 KB)
- DRAFT Guide for Submitting Permit Applications for Microorganisms
- SOP Template for APHIS BRS Plant Permits
- SOP Template for APHIS BRS Modified Microbe Movement Permits
Additional Guides and Resources
- Additional Regulatory Requirements for Authorizations (208.15 KB)
- APHIS eFile Training Resources
- BRS User’s Guide: General Document Preparation Guidelines for Submission to BRS
- Minimum Separation Distances to be used for Confined Field Tests of Certain Genetically Engineered Plants
- APHIS Recommendations for Best Management Practices for Authorized Field Trials of Regulated Herbicide-Resistant Crops
- List of Petunia Varieties
Download All BRS Permits and Notifications Data
- Download all BRS Permit and Notification data from APHIS eFile in csv file (2.11 MB)
- Download all BRS Permit and Notification data from ePermits in csv file (14.79 MB)
Paper Application
APHIS Form 2000 (67.52 KB)
Mail to: APHIS Biotechnology Regulatory Services, Permit Staff
4700 River Rd., Unit 78
Riverdale, MD 20737
- Notification Guide (693.77 KB)
- Guide for Submitting Confidential Business Information (315.59 KB)
- Am I Regulated (AIR) Process Guide for Submission of AIR Inquiries (165.96 KB) (165.96 KB)
- Am I Regulated Letters of Inquiry Table
- BRS User’s Guide: General Document Preparation Guidelines for Submission to BRS (150.13 KB) (150.13 KB)
- Guide for Submitting Confidential Business Information (315.59 KB) (315.59 KB)
- Questions and Answers (143.59 KB) (143.59 KB)
Exemptions and Confirmations
The regulations enabling the Exemptions and Confirmations process were vacated on Dec. 2, 2024, by a court order. Responses to confirmation requests issued before Dec. 2, 2024, remain valid.
Regulatory Status Reviews
The regulations enabling the Regulatory Status Review process were vacated on Dec. 2, 2024, by a court order. Responses to Regulatory Status Reviews issued before Dec. 2, 2024, remain valid.
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