New World Screwworm

Last Modified: June 03, 2024
Screwworm fly with orange eyes and a dark metallic-blue colored body sitting on a green leaf.

New World screwworm (NWS) infestation occurs when NWS fly larvae (Cochliomyia hominivorax) infest the flesh of living mammals and, less commonly, birds. USDA eradicated NWS from the United States in 1966 using sterile insect technique, a method where sterile flies are released in the wild. Today, NWS is endemic in Cuba, Haiti, the Dominican Republic, and countries in South America. There is a constant risk of introduction into the United States.

The name screwworm refers to the maggots' (larvae) feeding behavior as they burrow (screw) into the wound, feeding as they go like a screw being driven into wood. Maggots cause extensive damage by tearing at the hosts’ tissue with sharp mouth hooks. The wound can become larger and deepen as more maggots hatch and feed on living tissue. As a result, NWS can cause serious, often deadly damage to the animal.

Adult screwworm flies are about the size of a common housefly (or slightly larger). They have orange eyes, a metallic blue or green body, and three dark stripes along their backs.

Report mammals and birds with the following signs:

  • irritated behavior
  • head shaking
  • the smell of decay
  • evidence of fly strike
  • presence of fly larvae (maggots) in wounds

The best way to keep screwworm out of this country is to prevent introductions. NWS can infest mammals, including people, and birds. Here are steps you can take to avoid infestation:

  • Be alert for NWS symptoms in pets and livestock
  • Ensure that pets traveling internationally are inspected for screwworm
  • Check your vehicle for screwworm flies if you are in an NWS-infested area

If you think you have found a screwworm, report it immediately to your State animal health official and APHIS office. This will allow APHIS and partner agencies to respond quickly and remove the screwworms before a population becomes established.

Eradicating NWS is only possible through sterile insect technique. With this method, sterile flies are released into an area where a known population has become established. The sterile male screwworm flies mate with fertile female screwworm flies, causing the population of screwworm flies to decrease until it eventually dies out.

Animals infested with NWS should be treated according to the recommendations of their veterinarian. People who suspect they are infested with NWS should seek immediate medical treatment following the Centers for Disease Control and Prevention guidelines.

Report Signs of Animal Disease

Producers or owners who suspect an animal disease should contact their veterinarian to evaluate the animal or herd. Find an accredited veterinarian.

Animal health professionals (veterinarians; diagnostic laboratories; public health, zoo, or wildlife personnel; and others) report diagnosed or suspected cases of nationally listed reportable animal diseases to APHIS Area Veterinarians in Charge and to the State animal health official as applicable under State reporting regulations. 

Related Resources

There are currently no known established populations of screwworm flies in the United States.

Through our International Services program, we cosponsor a sterile fly release program in Panama to maintain a biological barrier in the region and protect screwworm-free areas in North and Central America

In 2016, USDA confirmed an established population of NWS in Key Deer located on Big Pine Key, FL. USDA partnered with the U.S. Fish and Wildlife Services (FWS), Florida Department of Agriculture and Consumer Services, and Florida’s Monroe County to prevent the spread of NWS, preserve the endangered deer, and protect domestic animals and pets. In 2017, USDA announced the successful eradication of NWS from Florida. Read more about the response below.

Sterile Fly Release

The USDA used a proven method for eradicating NWS fly populations that took advantage of the fly’s biology. Female screwworm flies mate one time in their 21-day lifespan. We released approximately 3 million sterile flies twice a week in the affected Florida Keys area. As the population of sterile NWS flies increased, fertile NWS flies decreased until the population died out. The USDA continued releasing sterile flies until there were no new clinical cases, and they eliminated the population of NWS flies.

The USDA continues to use this strategy to combat invasive species.

Screwworm Fly Surveillance

APHIS International Services worked with colleagues from Panama to monitor the success of the NWS fly eradication strategy. The team captured flies from across the Florida Keys and determined if they were sterile or fertile.

No fertile flies were found outside the infested zone in the lower Florida Keys, indicating a successful eradication strategy.

Animal Health Checkpoint

A mandatory animal health checkpoint was established at Mile Marker 106 in Key Largo to prevent NWS from leaving the Keys on pets or livestock.

Travelers with livestock or pets had to stop at the checkpoint and report any signs consistent with NWS. A veterinarian was assigned to the checkpoint to examine all suspect animals. The checkpoint was also a source of community outreach and education about NWS, the local infestation, the eradication strategy, and preventive measures to protect livestock and pets.

More than 6,000 animals traveled through the checkpoint; none were affected by NWS.

Animal Reports and Response

The USDA and Florida Department of Agriculture responded to reports of suspect wildlife, livestock (including poultry), and pets with clinical signs consistent with NWS infestation. There were no cases in livestock in the Keys, mainland, or outside of the infested Key islands.

Key Deer Monitoring and Response

The FWS, USDA, and the Florida Department of Agriculture and Consumer Services made significant efforts to protect endangered Key deer and other wildlife from infestation. The response focused on locating infested deer and administering medication, treating mild and moderate wounds by trained wildlife veterinarians, and in advanced cases, euthanizing deer for the animal’s welfare and to protect the remaining healthy deer and other wildlife.

FWS personnel and trained Refuge volunteers administered doramectin, an anti-parasitic medicine, to treat Key deer as a preventative measure. Additionally, FWS erected 27 self-medication stations in backcountry areas inaccessible to staff and volunteers. These self-medication stations became the main method of doramectin administration.

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