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Animal and Plant Health Inspection Service
U.S. Department of Agriculture
USDA FAQ's and resources about coronavirus (COVID-19).  LEARN MORE

Disinfectants

Veterinary Services protects and improves the health, quality, and marketability of our nation's animals, animal products and veterinary biologics by preventing, controlling and/or eliminating animal diseases, and monitoring and promoting animal health and productivity. Chemical disinfectants assist in protecting animal health by inactivating microbes on hard nonporous surfaces that cause disease in animals.

The table below lists various documents that can help government agencies and the public choose appropriate disinfectants to use against animal disease causative agents. This is a living document and is periodically updated to reflect the most current information. For questions or concerns regarding this document, please send an email message to vs.sp.disinfectants@usda.gov.

The biosecurity officer of the USDA APHIS or state partner incident management team responding to a foreign animal disease incident should use, as their first recourse, a commercially available U.S. Environmental Protection Agency (EPA)-registered disinfectant according to the directions on its container label (i.e, a Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) section 3 registration1). If a suitable commercially available EPA-registered disinfectant is not available, only then may a suitable disinfectant approved for use under a FIFRA section 18 registration2 be used according to its FIFRA section 18 label. Biosecurity officers should have with them a paper or electronic copy of the section 18 label and ensure that section 18 disinfectants are prepared and applied according to this section 18 label. Biosecurity officers using a section 18 disinfectant must record the amounts used and report this monthly to vs.sp.disinfectants@usda.gov.

Disinfectants for Use Against Animal Disease Causative Agents
Disease Agent Active Ingredient or Disinfectant Document Type Use Sites Document Title Document Date
African Swine Fever Virus Multiple Table Multiple Disinfectants Approved for Use Against African Swine Fever Virus in Farm Settings 09-2020
African Swine Fever Virus, Avian Influenza Virus, Foot and Mouth Disease Virus Citric acid FIFRA section 18 label Hard, nonporous, and porous food and nonfood surfaces Citric Acid Against FMDv, ASFv, and AIv; Section 18 Authorization Label  02-2019
African Swine Fever Virus, Classical Swine Fever Virus, Foot and Mouth Disease Virus Sodium Hypochlorite FIFRA section 18 label Porous and non-porous surfaces on indoor or outdoor use sites Sodium Hypochlorite Against FMDv, ASFv, CSFv; Section 18 Authorized Label 09-2018
African Swine Fever Virus, Foot and Mouth Disease Virus AeroDis 7127 FIFRA section 18 label Hard nonporous surfaces inside and outside aircraft, as well as associated loading equipment including loading ramps AeroDis 7127 (Benefect) aircraft disinfectant against FMDv and ASFv; Section 18 Authorization Label 09-2020
Avian Influenza Virus: Highly Pathogenic Virkon S + Propylene Glycol FIFRA section 18 label Hard nonporous surfaces on poultry premises in freezing temperatures Virkon S with Propylene Glycol Against HPAIv; Section 18 Authorization Label  01-2019
Avian Influenza Virus Multiple Table Multiple Potential Disinfectant Registered by USEPA For Use Against Avian Influenza  12-2018
Foot and Mouth Disease Virus Acetic acid FIFRA section 18 label Hard, non-porous, food/feed and non-food/feed surface Acetic Acid Against FMDv; Section 18 Authorized Label  05-2018
Foot and Mouth Disease Virus Multiple Table Multiple Disinfectants Approved for Use Against FMDv 10-2020
Foreign Animal Disease Agents Multiple Table Multiple  Potential Disinfectants to Use Against Foreign Animal Disease Agents in Farm Settings  01-2020
Newcastle Disease Virus Virkon S + Propylene glycol FIFRA section 18 label Hard nonporous surfaces on poultry premises in freezing temperatures Virkon S with Propylene Glycol Against NDv; Section 18 Authorized Label  12-2019
Newcastle Disease Virus Multiple Table Multiple Potential Disinfectants Registered for Use Against Newcastle Disease Virus in Farm Settings 11-2019
Newcastle Disease Virus Sodium hypochlorite + Propylene glycol FIFRA section 18 label Hard nonporous surfaces on poultry premises in freezing temperatures Sodium Hypochlorite with Propylene Glycol Against NDv; Section 18 Authorized Label 11-2019
Not applicable Not applicable Table Not applicable State Pesticide Licensing/Certification Requirements When Using Disinfectants in Animal Disease Outbreak 05-2019
Mycobacterium spp. Multiple Table Multiple Potential U.S. EPA registered disinfectants for use against Mycobacterium Spp. on farm settings in the United States   02-2019
Spring Viremia of Carp Virus
Tilapia Lake Virus
Multiple Table Multiple Potential Disinfectants to Use Against SVCV and TiLV 08-2021

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1 FIFRA section 3 registrations: section 3 of FIFRA authorizes EPA to register pesticides for use throughout the United State. For more information see Types of Registrations under FIFRA.
2 FIFRA section 18 registrations: section 18 of FIFRA authorizes EPA to allow emergency exemptions (also called section 18s) for the unregistered use of pesticides to address emergency conditions. For more information see Types of Registrations under FIFRA.

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