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Animal and Plant Health Inspection Service
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Regulatory Status Review Table

The table below provides regulatory status review (RSR) requests submitted to APHIS and APHIS’ corresponding responses.


 

RSR Number

Requestor

Plant (Common Name)

Scientific Name

Trait

Phenotype

MOA

Response Date

RSR Request

RSR Response

21-257-01rsr Infinite Enzymes, Inc.
Corn
Zea mays
Altered peroxidase and Herbicide Resistance
Manganese peroxidase production and Resistance to glufosinate
Embryo-preferred expression of manganese peroxidase and PAT (phosphinothricin N-acetyltransferase) confers resistance to glufosinate by catalyzing the conversion of L-phosphinothricin (L-PPT) to a non-phytotoxic form (N-acetylphosphinothricin).
10/20/2022 View Document View Document
21-270-01rsr
J. R. Simplot Company
Potato
Solanum tuberosum
Altered tuber quality, Altered tuber sugar profile, Herbicide resistance, Fungal resistance, and Virus resistance, Resistance to potato late blight,
Reduced black spot, Reduced glucose and fructose content in tubers, Resistance to ALS/AHAS inhibitor herbicides, Resistance to potato late blight and Resistance to Potato virus Y (PVY)

Tuber specific RNAi mediated silencing of Ppo5 (polyphenol oxidase-5) gene; Tuber-specific RNAi mediated silencing of VInv (vacuolar invertase) gene decreases VInv protein expression, resulting in less hydrolysis of sucrose to glucose and fructose; An insensitive form of Acetolactate synthase (ALS)/Acetohydroxy acid synthase (AHAS) with a decreased binding affinity to certain ALS/AHAS inhibitor herbicides; Expression of three resistance genes to Phytophtora infestans: (Rpi) Rpi-vnt1, Rpi-amr3, Rpi-blb2 encoding resistance (R) proteins that recognize effector protein secreted by Phytophthora infestans and signal a hypersensitive response that destroys infected tissue through programmed cell death, restricting growth and spread of the pathogen to other parts of the plant; and RNAi mediated silencing of PVY coat protein gene


10/20/2022 View Document View Document
21-166-01rsr Norfolk Plant Sciences
Tomato
Solanum lycopersicum
Product Quality and Marker Gene
Purple fruit color and increased anthocyanin in fruits, resistance to kanamycin and neomycin Fruit-specific expression of the Antirrhinum majus Del and Ros1 transcription factors, Neomycin phosphotransferase (NPTII) 09/06/2022 View Document View Document
21-152-01rsr Agrivida, Inc.
Corn Zea mays
Altered enzyme levels and Marker gene (carbon source)
Increased beta-glucanase and carbon source (Mannose) used as a selectable marker
Seed-specific expression and endoplasmic reticulum localization of a thermostable beta-glucanase that hydrolyzes glycosidic bonds of glucans and mannans and PMI (phosphomannose isomerase) catalyzes the reversible conversion of mannose 6-phosphate and fructose 6-phosphate.
09/29/2022 View Document View Document
21-245-01rsr ToolGen
Potato
Solanum tuberosum
Altered tuber quality
Reduced enzymatic browning
Knockout of a polyphenol oxidase gene (StPPO2) expressed primarily in tubers
9/29/2022 View Document View Document


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