Insects and Mites FAQ's

Last Modified: March 24, 2025

You must have a PPQ 526 permit to move ALL wild-type plant pests including biological control organisms within the United States and its Territories whether they occur in the destination State or not. If the organism is on the list of organisms approved for interstate movement by regulation,  you do not need a PPQ 526 permit to move it within the contiguous United States if there are no contaminants such as other organisms, parasitoids, plant material, or pathogens. However, you must have a PPQ 526 permit to move organisms on the list to Hawaii and U.S. Territories. APHIS Plant Protection and Quarantine (PPQ) regulates wild-type arthropods; APHIS Biotechnology Regulatory Services (BRS) oversees the regulation of modified arthropods. If you are moving a genetically engineered (GE) arthropod plant pest, you must obtain an interstate movement or release permit from APHIS BRS. 

Important: Your permit application should only include wild-type or GE arthropod plant pests, not both.

The level of containment depends on the species, geographic distribution, and intended use. Widely distributed organisms may require little or no containment. However, if you plan to import or move interstate an exotic organism that may be a pest, including biological control organisms, into an area of the United States in which it does not occur or could easily establish, you may be required to move the organism into a containment facility. Import or interstate movement of nonindigenous organisms may require a containment facility that has been inspected and approved by APHIS PPQ before they can be moved. APHIS considers the following risk factors, but not limited to, when evaluating the necessary level of containment facilities:

  • Organism’s life cycle and reproductive rate
  • Organism’s size and dispersal ability
  • Purpose of the movement, such as proposed activities in laboratories, growth chambers, or greenhouses
  • Whether the organism is indigenous to the United States and the area where you plan to move it
  • Life stage required for movement
  • Host availability
  • Competition with native or beneficial species
  • Survivability outside containment facilities
  • Potential for the organism to be parasitized or infected with pathogens or contaminated with other organisms
  • Whether you plan to maintain a colony, isolate, or destroy upon arrival

Most dead arthropods do not require a PPQ 526 permit, except as follows:

  • For the superfamily Apoidea (bees), notification of importation of dried or preserved specimens must be received at least 10 days prior to arrival, per 7 CFR part 322.
  • Trogoderma granarium (Dermestidae), per 7 CFR part 330 (§ 330.106 (a)).
  • Dead arthropods for isolating or extracting microbes or making infectious clones of arthropod pathogens, plant pathogens, or biocontrol organisms must be accompanied by a PPQ 526 microbial permit for biological research.

Under 7 CFR 330.200, "biological specimens of plant pests, in preservation or dried, may be imported without further restriction under this part, but subject to inspection on arrival in the United States to confirm the nature of the material and freedom from risk of plant pest dissemination". Packages must not contain any plant material, soil, or other plant pests and are subject to inspection by Customs or USDA officials at the port of entry. In addition, the importer is responsible for complying with other Federal or State requirements (e.g. Environmental Protection Agency, U.S. Fish and Wildlife Service, etc.). Please note that a completed U.S. Fish and Wildlife Service Form 3-177 should accompany shipments at the point of entry.

In general, the receiver should apply for the permit since it is his or her responsibility to handle or contain the shipped organism. The exception to this is when a commercial entity is moving organisms for sale within the United States, particularly when the movement is to multiple States for retail sale or use.

  • All shipments of Drosophila flies into the United States and U.S. Territories from foreign sources must be pre-authorized with a PPQ 526 permit.
  • Drosophila melanogaster interstate shipments among States in the continental United States (including Alaska) do not require a PPQ 526 permit.
  • Interstate shipments of Drosophila spp. to and from Hawaii and U. S. Territories require permits and containment. 

Drosophila fly shipments manifested as “fruit flies” have raised agricultural and environmental concerns because this common name refers to notoriously significant plant pests like the Mediterranean and oriental fruit flies. As a result, a PPQ 526 permit is required so that shipments are appropriately routed to PPQ inspection stations to confirm the identities of the enclosed organisms, intercept undesired pests, or apply appropriate treatment, etc. Import permits and the appropriate use of shipping labels will facilitate movement through Customs and Border Protection inspection processes and minimize delays in PPQ inspection stations.