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Animal and Plant Health Inspection Service
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APHIS Permits (ePermits and eFile)

Access APHIS ePermits Access APHIS eFile

As of September 30, 2022, APHIS eFile is the exclusive online system for users to apply for and receive import, interstate movement, transit, and release permits, apply for permit renewals and amendments, submit annual reports, and receive regulatory guidance. For information regarding Animal Care licensing and registrations, please refer to our information page.

ePermits is APHIS’ legacy permitting system, and as of September 30, 2022, APHIS will no longer accept new permit applications or issue renewals through ePermits. All active permits issued through ePermits will remain valid, and eligible for amendment, until permit expiration. No ePermits data will be moved into APHIS eFile. You will need to submit a new application in APHIS eFile when any of your ePermits permits expire.

Animal and Animal Products

Includes live animals, semen, embryos and materials derived from animals or exposed to animal-source materials such as animal tissues, blood, cells or cell lines of livestock or poultry origin, RNA/DNA extracts, hormones, enzymes, microorganisms including bacteria, viruses, protozoa, and fungi. In addition, animal materials including dairy products (except butter and cheese), and meat products (e.g., meat pies, prepared foods) from countries with livestock diseases exotic to the U.S.

If you are importing a pet dog or cat, please do not apply for an import permit and contact the Centers for Disease Control and Prevention (CDC) for requirements.


Live Dogs (resale or research)

If you are importing live dog(s) for resale, whether through commercial sale or adoption, please visit How to Bring Dogs into the United States for Commercial Sale or Adoption for important information about live dog imports. 

Biotechnology Permits

Includes genetically engineered organisms considered to be regulated articles.

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