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Microbial Organisms Used to Control Invertebrate Plant Pests and Plant Pathogens

Under the authority of the Plant Protection Act of 2000, APHIS Plant Protection and Quarantine (PPQ) 526 permits are required for the importation, interstate movement, and environmental release of biological control organisms and biopesticides for plant pests, diseases, and weeds. Often the organisms are not plant pathogens, but their potential effects on beneficial organisms could indirectly affect plant health.  This policy refers to biopesticide microbial organisms that control invertebrate plant pests and microbial plant diseases (pathogens).  Permits may be required for foreign isolates of microorganisms even if the species and genus is present in the environment of the United States.

APHIS-Biotechnology Regulatory Service (BRS) regulates and issues permits for genetically engineered microorganisms.  For more information or to contact BRS for guidance go to the BRS Website.  

Permits are required for the following:

Importation of microorganisms for research
Importation of microorganisms registered by the U.S. Environmental Protection Agency (EPA) for commercial use or research authorized by Experimental Use Permits.

Permit Requirements

Foreign microbial strains
Soil to isolate microorganisms
Domestically isolated microbial strains
Export and import of microorganisms
EPA-registered biopesticides
Importation of organisms that may not be plant pathogens, biopesticides, or biocontrol organisms
Importation of products such as foreign soil amendments, biofertilizers, growth enhancers, plant health promoters, biostimulants, composts or similar materials that contain unidentified microorganisms and unauthorized substrates for environmental release
Questions for field releases (<10 acres) of microbial biological control organisms of foreign origin
Complementary Content