APHIS regulates the introduction (importation, interstate movement, or environmental release) of certain genetically engineered (GE) organisms. All regulated introductions of GE organisms must be authorized by APHIS under either its permitting or notification procedures. When a developer has collected enough evidence that a GE organism poses no more of a plant pest risk than an equivalent non-GE organism, the developer may petition APHIS for a determination of non-regulated status. If the petition is approved by APHIS, the GE organism may then be introduced into the United States without any further APHIS regulatory oversight. Guidance for these application processes can be found at the links below.