United States Department of Agriculture
Animal and Plant Health Inspection Service
Tuberculosis in Elephants
Tuberculosis in Elephants: Science, Myths and Beyond!
APRIL 5 – 6, 2011
USDA, APHIS Center for Animal Welfare
Kansas City, MO
AGENDA
| April 5, 2011 | |||
| Time | Session | Topic | Speaker |
| 8:00 | Welcome | Chester Gipson, Deputy Administrator, Animal Care | |
| 8:30 | Session I: Overview and History of TB | KEYNOTE: Global and U.S. Tuberculosis Epidemiology and Principles of Control | Philip LoBue, MD, FACP, FCCP, Associate Director for Science of the Division of Tuberculosis Elimination (DTBE) at the Centers for Disease Control and Prevention |
| A Brief History of TB in Elephants | Susan K. Mikota, DVM, Elephant Care International | ||
| 9:45 | BREAK | ||
| 10:00 | Session II: TB Immunology & Pathophysiology | Comparative immunology of tuberculosis in various hosts | Ray Waters,DVM, National Animal Disease Center, Agricultural Research Service |
| Cellular immune responses to Mycobacterial infection in Asian Elephants (schedule change – see 4/6 AM) Molecular Genetic Study of Tuberculosis in Elephants | Jennifer (Jaime) A. Landolfi, DVM, Diplomate ACVP University of Illinois Zoological Pathology Program (ZPP) and Veterinary Diagnostic Laboratory (VDL) William S. Modi, PhD | ||
| Session III: Current Technologies to Diagnose TB in Elephants | TB Culture: Advantages and Limitations | Suelee Robbe-Austerman, DVM, PhD, Mycobacteria/Brucella Lab, National Veterinary Services Laboratories | |
| Serological Testing: Data on Elephant TB Stat-Pak, MAPIA, and DPP | Konstantin Lyashchenko, PhD, Senior R&D Director, Chembio Diagnostic Systems, Inc. | ||
| 11:30 | LUNCH | ||
| 12:45 | Session III: Current Technologies to Diagnose TB in Elephants (cont.) | DNA extraction techniques from Trunk Washes | Lindsey Linke, Research Associate, Animal Population Health Institute, CO State University |
| Novel diagnostic test for the detection of latent tuberculosis | Fred Quinn, PhD, Department of Infectious Diseases College of Veterinary Medicine University of GA | ||
| Postmortem Examination Procedures | Rita McManamon, DVM, Infectious Disease Laboratory, Dept. Small Animals Medicine & Surgery, Dept. Veterinary Pathology, University of GA, College of Veterinary Medicine | ||
| Lessons from "Mycobacterium-related" Elephant Necropsy Cases | Scott P. Terrell, DVM, Diplomate ACVP, Veterinary Pathologist and Operations Manager, Department of Animal Health, Disney's Animal Programs and Environmental Initiatives; Clinical Assistant Professor, Infectious Diseases and Pathology, University of Florida College of Veterinary Medicine | ||
| 2:20 | BREAK | ||
| 2:35 | Session IV: Epidemiology of TB | Epidemiology of Tuberculosis in Elephants, 1994-2011 | Kathleen Orloski, DVM, MS, Diplomate, ACVPM, Epidemiology Specialty USDA, APHIS, Veterinary Services, TB Eradication Program |
| Session IV: Epidemiology of TB(cont.) | Discordance between USDA administered Chembio ElephantTB StatPak® tests and MAPIATM results for tuberculosis in Asian elephants (Elephas maximus) | Ramiro Isaza, DVM, Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of FL, Gainesville | |
| 3:45 | BREAK | Role of molecular testing in elephant TB diagnosis | James Higgins, PhD, Mycobacteria and Brucella Section of the National Veterinary Services Laboratories, USDA- APHIS |
| 4:00 | PANEL | Moderated | Speakers from Day 1 |
| 5:00 | END of DAY 1 | ||
| April 6, 2011 | |||
| Time | Session | Topic | Speaker |
| 8:00 | ANNOUNCEMENTS | ||
| 8:20 | Session II (rescheduled from Day 1) | Cellular immune responses to Mycobacterial infection in Asian Elephants | Jennifer (Jaime) A. Landolfi, DVM, Diplomate ACVP University of Illinois Zoological Pathology Program (ZPP) and Veterinary Diagnostic Laboratory (VDL) |
| Session V – Public Health Issues and Zoonotic Concerns | Transmission of TB Between Elephants and Humans: a Review of Published Studies | Joel Maslow, MD, PhD, Division of Infectious Diseases, Veterans Administration Medical Center and University of PA School of Medicine | |
| Outbreak of MTb among Employees at an Elephant Facility | Rendi Murphree, PhD, CDR, USPHS,CDC Epidemic Intelligence Service Officer, TN Department of Health | ||
| 9:35 | BREAK | ||
| 9:55 | Session V – Public Health Issues and Zoonotic Concerns (cont.) | Risk Assessment and Zoonotic Implications | Yvonne Nadler, DVM, MPH, Veterinary Epidemiologist, Program Manager, Zoo Animal Health Network, Lincoln Park Zoo |
| NIOSH Approach to a TB Outbreak | Todd Niemeier, MS, IH,Industrial Hygienist, CDC/NIOSH,Division of Surveillance, Hazard Evaluations and Field Studies | ||
| Session VI: Treatment of Elephants for Tuberculosis | History and Review of Current Treatment Protocols | Joel Maslow, MD, PhD, Division of Infectious Diseases, Veterans Administration Medical Center and University of PA School of Medicine | |
| Sourcing, formulating and administering TB drugs | Dan Loper, R.Ph, DVM, Grove Pharmacy, Springfield, MO | ||
| 11:30 | LUNCH | ||
| 12:45 | Session VI: Treatment of Elephants for Tuberculosis (cont.) | A Fifteen Year (1996-2011) Review of Treatment Modalities and Outcomes Utilizing Anti-Tuberculosis Antibiotics in Elephants | Dennis Schmitt DVM, PhD, Diplomate ACT, Ringling Bros. Chair of Veterinary Care, Director of Research and Conservation |
| Challenges to Treatment and Possible Side Effects | Genevieve Dumonceaux, DVM, Palm Beach Zoo, West Palm Beach, FL | ||
| Session VII: Guidelines | Evolution of The Guidelines for the Control of Tuberculosis in Elephants | Janet Payeur, Director of Scientific Outreach, National Veterinary Services Laboratory, APHIS, USDA | |
| 2008 and 2010 Guidelines for the Control of Tuberculosis in Elephants – Rationale for changes to management groups | Chuck Massengill, DVM, CRM Veterinary Consulting, California, MO AND Michele Miller, DVM, Palm Beach Zoo, West Palm Beach, FL | ||
| 2:30 | BREAK | ||
| 2:45 | PANEL | Moderated | All Available Speakers Day 1 & 2 |
| 3:45 | BREAK | ||
| 4:00 | PANEL (cont.) | ||
| 5:00 | END of SEMINAR | ||