African swine fever (ASF), first described in the 1920s in Kenya, is a highly contagious hemorrhagic disease of wild and domestic suids with extremely high morbidity and mortality rates. ASF is a notifiable disease with the World Organization for Animal Health (OIE) due to its ability to spread rapidly and cause severe illness. ASF does not pose a risk to public health. ASF is unique, as it is the only known arthropod-borne, DNA virus. The disease is endemic in Sardinia, most countries of sub-Saharan Africa, and some West African countries. Spain and Portugal eradicated ASF in the mid-1990’s; it was also eradicated from the Caribbean following outbreaks from 1977–1980. However, the unimpeded spread of ASF through Russia, the Caucasus and recent introduction into China is cause for concern. ASF has never been reported in the United States, Canada, Australia, or New Zealand.