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Animal and Plant Health Inspection Service
U.S. Department of Agriculture

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April 5, 2021 - BRS Permit Applicants Required to Use APHIS eFile


On April 5, 2021, all applicants for permits from the United States Department of Agriculture’s Animal and Plant Health Inspection Service (APHIS), Biotechnology Regulatory Services (BRS) will be required to apply using APHIS eFile. 

We encourage you to create your APHIS eFile account today to apply for BRS permits at: https://efile.aphis.usda.gov/  

Five Things to Know Now

  1. Consistent with the revised regulations found at 7 CRF part 340, notifications will no longer be available after April 4, 2021.
  2. ePermits remains available for access to past BRS permits and notifications, and for submission of PPQ and VS permits. Application data from ePermits will not be available in APHIS eFile.
  3. Any applications submitted in ePermits through April 4, 2021, will be processed in ePermits. Compliance reports related to these applications must be submitted in ePermits.
  4. BRS will reject any applications submitted in ePermits on and after April 5, 2021.
  5. Courtesy permits are not available in APHIS eFile.  


APHIS eFile Webinar Training Sessions

Virtual training will be available to support your transition to APHIS eFile during the weeks of April 5, 2021 and April 12, 2021. If you are unable to participate in training, recordings of the trainings will be available for viewing on the BRS website. Learn more and register at the link below.


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