National Wildlife Research Center (NWRC)

Development of Reproductive Control Methods for Overabundant Birds and Mammals

PROJECT GOALS: To obtain U.S. Environmental Protection Agency (EPA) approval for use of PZP and GnRH immunocontraceptive vaccines for white-tailed deer and to develop new oral contraceptive agents for use in controlling reproduction in overabundant avian species, such as monk parakeets and crows, and in mammalian species, such as California ground squirrels and prairie dogs.

Objective 1: Register GnRH/AdjuVac and SpayVac/AdjuVac with the EPA for use in white-tailed deer and develop off-label use plans for other species.

Objective 2: Develop an oral or non-injectable GnRH vaccine (as an alternative to the injectable vaccine) for rodents and feral pigs. Develop yeast as a vector to deliver either the GnRH or rodent PZP contraceptive vaccines orally.

Objective 3: Develop and begin the EPA-approval process for one or more effective oral contraceptive compounds for potential use in avian species, such as monk parakeets and crows, and rodent species, such as ground squirrels and prairie dogs.

Objective 4: Determine feasibility of developing a species-specific anti-conceptus vaccine.

Project Home Page
Project Goals and Objectives
Accomplishments
Publications
GonaCon™
GnRH Immunocontraception (Technical Discussion)
Adjuvant Development (Technical Discussion)
Conjugate Design (Technical Discussion)
Nicarbazin
Diazacon
PZP