West Nile Virus
VS,
along with the CDC,
the U.S.
Geological Survey, State wildlife agencies, and State and local
health and vector control agencies, make up the West Nile Virus
(WNV) Surveillance System. In FY 2002, the number of equine cases
of WNV and the geographic spread of the disease increased dramatically.
There were 8,063 cases of the virus in 40 states in FY 2002. Generally,
one in 3 cases of WNV in equines results in death, which translated
into approximately 2,700 deaths in FY 2002.
The WNV Surveillance System is intended to monitor the geographic
spread of WNV over the contiguous United States; to further develop
national public health strategies for WNV surveillance, prevention,
and control; to develop a more complete regional picture of the
geographic distribution and incidence of similar viruses; and to
provide national and regional information to public health officials,
elected government officials, and the public.
As part of the ongoing effort to diagnose FADs
in the United States, specially trained FAD diagnosticians investigate
suspect cases of neurological illness in equines. In FY 2002, 190
investigations were carried out on equines with neurological illness.
Since late 1999, such equines have usually been tested for WNV infection
at the NVSL.
NVSL performs primary WNV testing
on equine submissions from private veterinary practitioners, veterinary
teaching hospitals, and laboratories in States without WNV testing
capability. It also does confirmatory testing in support of State
veterinary diagnostic laboratories where screening tests for WNV
are performed, and provides training on WNV testing protocols for
state veterinary diagnostic personnel.
In FY 2002, NVSL conducted nearly 10,200 tests on serum (blood)
samples or on cerebrospinal fluid samples, and nearly 900 WNV tests
on tissue samples (most frequently equine brain tissues). These
test counts do not include additional testing that may have been
performed with some samples to examine for evidence of other diseases
such as eastern equine encephalomyelitis or western equine encephalomyelitis.
Since the detection of WNV in the United States in 1999, VS has
worked to facilitate development of an equine WNV vaccine. In August
2001, it granted a conditional license for a WNV vaccine to Fort
Dodge Animal Health (a division of Wyeth). To date, more than six
million doses of the killed virus product have been distributed
to veterinary practitioners nationwide. Vaccination requires two
doses in the initial year followed by an annual booster.
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