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Tuberculosis in Elephants: Science, Myths and Beyond!

APRIL 5 – 6, 2011
USDA, APHIS Center for Animal Welfare
Kansas City, MO

AGENDA

April 5, 2011
Time Session Topic Speaker
8:00 Welcome Chester Gipson, Deputy Administrator, Animal Care
8:30 Session I: Overview and History of TB KEYNOTE: Global and U.S. Tuberculosis Epidemiology and Principles of Control Philip LoBue, MD, FACP, FCCP, Associate Director for Science of the Division of Tuberculosis Elimination (DTBE) at the Centers for Disease Control and Prevention
A Brief History of TB in Elephants Susan K. Mikota, DVM, Elephant Care International
9:45 BREAK
10:00 Session II: TB Immunology & Pathophysiology Comparative immunology of tuberculosis in various hosts Ray Waters,DVM, National Animal Disease Center, Agricultural Research Service
Cellular immune responses to Mycobacterial infection in Asian Elephants (schedule change – see 4/6 AM) Molecular Genetic Study of Tuberculosis in Elephants Jennifer (Jaime) A. Landolfi, DVM, Diplomate ACVP University of Illinois Zoological Pathology Program (ZPP) and Veterinary Diagnostic Laboratory (VDL) William S. Modi, PhD
Session III: Current Tech-nologies to Diagnose TB in Elephants TB Culture: Advantages and Limitations Suelee Robbe-Austerman, DVM, PhD, Mycobacteria/Brucella Lab, National Veterinary Services Laboratories
Serological Testing: Data on Elephant TB Stat-Pak, MAPIA, and DPP Konstantin Lyashchenko, PhD, Senior R&D Director, Chembio Diagnostic Systems, Inc.
11:30 LUNCH
12:45 Session III: Current Tech-nologies to Diagnose TB in Elephants (cont.) DNA extraction techniques from Trunk Washes Lindsey Linke, Research Associate, Animal Population Health Institute, CO State University
Novel diagnostic test for the detection of latent tuberculosis Fred Quinn, PhD, Department of Infectious Diseases College of Veterinary Medicine University of GA
Postmortem Examination Procedures Rita McManamon, DVM, Infectious Disease Laboratory, Dept. Small Animals Medicine & Surgery, Dept. Veterinary Pathology, University of GA, College of Veterinary Medicine
Lessons from "Mycobacterium-related" Elephant Necropsy Cases Scott P. Terrell, DVM, Diplomate ACVP, Veterinary Pathologist and Operations Manager, Department of Animal Health, Disney's Animal Programs and Environmental Initiatives; Clinical Assistant Professor, Infectious Diseases and Pathology, University of Florida College of Veterinary Medicine
2:20 BREAK
2:35 Session IV: Epi-demiology of TB Epidemiology of Tuberculosis in Elephants, 1994-2011 Kathleen Orloski, DVM, MS, Diplomate, ACVPM, Epidemiology Specialty USDA, APHIS, Veterinary Services, TB Eradication Program
Session IV: Epi-demiology of TB(cont.) Discordance between USDA administered Chem-Bio ElephantTB StatPak® tests and MAPIATM results for tuberculosis in Asian ele-phants (Elephas maximus) Ramiro Isaza, DVM, Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of FL, Gainesville
3:45 BREAK Role of molecular testing in elephant TB diagnosis James Higgins, PhD, Mycobacteria and Brucella Section of the National Veterinary Services Laboratories, USDA- APHIS
4:00 PANEL Moderated Speakers from Day 1
5:00 END of DAY 1

April 6, 2011
Time Session Topic Speaker
8:00 ANNOUNCEMENTS
8:20 Session II (rescheduled from Day 1) Cellular immune responses to Mycobacterial infection in Asian Elephants Jennifer (Jaime) A. Landolfi, DVM, Diplomate ACVP University of Illinois Zoological Pathology Program (ZPP) and Veterinary Diagnostic Laboratory (VDL)
Session V – Public Health Issues and Zoonotic Concerns Transmission of TB Between Elephants and Humans: a Review of Published Studies Joel Maslow, MD, PhD, Division of Infectious Diseases, Veterans Administration Medical Center and University of PA School of Medicine
Outbreak of MTb among Employees at an Elephant Facility Rendi Murphree, PhD, CDR, USPHS,CDC Epidemic Intelligence Service Officer, TN Department of Health
9:35 BREAK
9:55 Session V – Public Health Issues and Zoonotic Concerns (cont.) Risk Assessment and Zoonotic Implications Yvonne Nadler, DVM, MPH, Veterinary Epidemiologist, Program Manager, Zoo Animal Health Network, Lincoln Park Zoo
NIOSH Approach to a TB Outbreak Todd Niemeier, MS, IH,Industrial Hygienist, CDC/NIOSH,Division of Surveillance, Hazard Evaluations and Field Studies
Session VI: Treatment of Elephants for Tuberculosis History and Review of Current Treatment Protocols Joel Maslow, MD, PhD, Division of Infectious Diseases, Veterans Administration Medical Center and University of PA School of Medicine
Sourcing, formulating and administering TB drugs Dan Loper, R.Ph, DVM, Grove Pharmacy, Springfield, MO
11:30 LUNCH
12:45 Session VI: Treatment of Elephants for Tuberculosis (cont.) A Fifteen Year (1996-2011) Review of Treatment Modalities and Outcomes Utilizing Anti-Tuberculosis Antibiotics in Elephants Dennis Schmitt DVM, PhD, Diplomate ACT, Ringling Bros. Chair of Veterinary Care, Director of Research and Conservation
Challenges to Treatment and Possible Side Effects Genevieve Dumonceaux, DVM, Palm Beach Zoo, West Palm Beach, FL
Session VII: Guidelines Evolution of The Guidelines for the Control of Tuberculosis in Elephants Janet Payeur, Director of Scientific Outreach, National Veterinary Services Laboratory, APHIS, USDA
2008 and 2010 Guidelines for the Control of Tuberculosis in Elephants – Rationale for changes to management groups Chuck Massengill, DVM, CRM Veterinary Consulting, California, MO AND Michele Miller, DVM, Palm Beach Zoo, West Palm Beach, FL
2:30 BREAK
2:45 PANEL Moderated All Available Speakers Day 1 & 2
3:45 BREAK
4:00 PANEL (cont.)
5:00 END of SEMINAR

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